Europa League champions Chelsea aim to fend off Arsenal for third place with victory over Everton at Stamford Bridge.
David Moyes takes charge of his final game at Goodison Park when West Ham United head to Merseyside on Sunday.
Liverpool are five points behind Everton going into Sunday's Merseyside derby at Anfield.
Everton look to tighten their grip on sixth place against Fulham at Goodison Park on Saturday.
After last weekend's dramatic Tyne-Wear derby victory, Mike Holden fancies Sunderland to see off Everton on Saturday.
Paolo Di Canio's tailor is on high alert once again as his Sunderland side prepare to face Everton at the Stadium of Light.
Arsenal remain on course for a top-four finish, but Tuesday evening's opponents Everton have European aspirations of their own.
Everton are one side refusing to go away in the hunt for Europe - can they continue their good form against QPR?
Tottenham Hotspur look to continue their Champions League charge against Everton at White Hart Lane on Sunday afternoon.
Everton hunt a third win on the spin at Goodison Park when Stoke City head to Merseyside on Saturday evening.
Everton were awful last weekend, but Mike Holden is backing them to bounce back by beating Manchester City at home on Saturday.
Everton still have European football on the agenda when Manchester City head to Goodison Park on Saturday afternoon
- @sammydymond Good to see a modern day Gary Sprake in action at The Emirates — 5 hours 41 min ago
- @GMPCityCentre What about the other three? — 16 hours 56 min ago
- Mark Hughes PL away record since 2008 between Sep 1st and St Geroge's Day: W1 D21 L38. But please, help yourself to the 13/5 Stoke tomorrow! — 19 hours 4 min ago
- But wait, it gets better... — 19 hours 8 min ago
- Mark Hughes' PL away record since Aug 2008: W8 D24 L45. Over £400 profit on level £10 lays (...can't be arsed working out 45 home wins!) — 19 hours 8 min ago